In Brief High-dose nutritional supplements operate on the assumption that more of a beneficial compound is always better — a pharmacological fallacy that ignores the homeostatic regulation that governs nutrient metabolism at physiological concentrations. Fat-soluble vitamins (A, D, E, K) and several minerals accumulate in tissue when supplemented above physiological need; toxicity from chronic high-dose […]
7 Critical Reasons Why Nutritional Supplements and Meals Aren’t Interchangeable
In Brief Nutritional supplements deliver isolated compounds. Whole foods deliver those compounds within a biological matrix of fiber, cofactors, and synergistic phytochemicals that fundamentally alter how nutrients are absorbed and metabolized. Eating is not merely fuel delivery. It is a sensory and physiological process that activates digestive enzyme secretion, gut motility, microbiome modulation, and — […]